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Genetic Predisposition A Likely Reason for Progression to AIDS Among Individuals with HIV

A new study at the University of Texas HealthScience Center in San Antonio were able to identity two specific genes that can be blamed for HIV-infected individuals’ predisposition to AIDS. Two genes that were identified during the study, CCR5 and CCL3L1, were the main culprit as to why some people are more likely to develop AIDS than others.

Previously, it was thought that viral loads (the amount of virus present in the blood), was the primary determinant why individuals who are infected with HIV will more likely to develop than any other individuals. The new study reveals a different story.

Individuals with specific combination of the two genes above which controls the entry of HIV particles into cells with CD4 markers (certain binding sites for T4 white blood cells) and works on cellular immune response respectively have greater chances of their health condition to worsen compared to other individuals who don’t. Read more at Science Daily.

This study was made possible by National Institute of Allergy andInfectious Diseases (NIAID) and was published at the October issue of Nature Immunology.

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